Top 10 Best Weight Loss Pills for Men (2024 Reviews & Guide)

Last Updated Feb 15, 2024

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What are the best weight loss pills for men? Better yet, why are they better for men than women? There are many reasons why a man can be overweight. Hormones, diet, activity level, stress, age, and genetics all play major roles in male weight.

Luckily for men, there are weight loss pills that work. Plus, they may even help motivate you to get back to looking like your old self or find a new self you never knew existed. In this guide, you’ll discover your best options as well as helpful tips and product reviews.

Let’s start with an overview of the supplements.

Top 10 Weight Loss Pills for Men

Product Description
#1) Modern Man V.3 Intense 2-in-1 Thermogenic & Testosterone Support

  • 2-in-1 Testosterone Booster and Thermogenic Fat Burner recommended for men over 40
  • KSM-66 Ashwaghanda® Extract, Longjack, and Coleus Forskohlii naturally boost testosterone to reduce belly fat
  • Trademarked Cocoabuterol™ from cacao seed to burn fat and promote muscle growth
#2) RSP Nutrition QuadraLean Thermogenic Fat Burner

  • A blend of appetite suppression, more energy, metabolism booster, thermogenic fat burner
  • Impressive before & after results by real men
  • Active ingredients CLA, L-Carnitine, and Paradoxine®
#3) Old School Labs Vintage Burn Muscle-Preserving Fat Burner

  • Safest and most effective weight loss supplement for men who care about body composition
  • Formulated to burn fat not muscle
  • 9 fat burners without any fillers or “proprietary” blends
  • Garcinia Fruit Extract, Raspberry Ketones, and Green Coffee Bean Extract
  • Non-GMO, Vegetarian, Gluten-Free, and Keto-Friendly
#4) Jacked Factory Burn-XT Thermogenic Fat Burner

  • Adequate amounts of effective fat burners
  • Green Tea Extract and Caffeine Anhydrous for an energy boost
  • Beat food cravings with appetite suppression
  • Boost your metabolism with cayenne pepper extract
  • No harsh fillers or other ingredients
#5) Iron Brothers Thermo Burn

  • A combination of Yohimbe HCL, Grains of Paradise, and Theobromine to accelerate a slow metabolism
  • Ingredients that target visceral fat
  • 275 mg of Caffeine anhydrous per serving
  • L-Theanine prevents caffeine jitters
#6) Dr. Emil Nutrition MaxBurn

  • An appetite-suppressing blend of Green Tea, Caffeine Anhydrous, Garcinia Cambogia, and Green Coffee Bean
  • Developed by a former professional athlete
  • More affordable than similar blends
  • Non-GMO 100% Natural Formula
#7) Hydroxycut Hardcore Elite

  • A highly affordable & effective thermogenic fat burner
  • Additional ingredients to boost focus
  • Easy-to-follow directions
  • Higher doses of Theobromine and Yohimbe
#8) MAV Nutrition Night Time Fat Burner

  • An effective sleep aid
  • Supports thermogenesis during sleep
  • Stimulant-Free
  • L-Theanine, L-Tryptophan, and Melatonin for a deeper, better night’s rest
  • Non-habit forming
#9) Prime Labs Prime Test

  • Helps to boost testosterone
  • Improves mood
  • A Stimulant-Free Energy Boost
  • Only natural testosterone boosters
  • May help to boost libido
#10) Nobi Nutrition Premium Night Time Fat Burner

  • Suppress an overactive appetite at night
  • Promotes a more restful night’s sleep for better recovery
  • No unnecessary fillers or additives
  • Valerian Root, Lemon Balm, and Passion Flower promote a sense of calm before bed
  • Boost thermogenesis in your sleep

Reviews: Best Weight Loss Pills for Men

Have you already chosen the best weight loss supplement for you? If you’re still on the fence, let our product reviews below help guide you.

In each review, we provide a brief summary of our thoughts and the pros & cons. We’re confident that by the end of our guide, you’ll be 100% certain which supplement is for you.

Modern Man V.3 Intense 2-in-1 Thermogenic & Testosterone Support

Modern Man V3 is an exciting all-in-1 testosterone booster and thermogenic fat burner. We love the no-nonsense ingredients in this blend. Weight loss pills have come a long way since they were chock-full of harmful ingredients that came with a bevy of nasty side effects.

Modern Man V3 is a 21st-century clean fat burner that’s safe and effective. Men who are over 40 and battling lower testosterone levels will benefit the most from this blend. However, younger men who are physically fit are also finding an edge with this supplement to achieve the chiseled six-pack abs of their dreams.

Overall, Modern Man V3 is a winner for any man who wants to boost T naturally, cut fat, and just feel better in general.

  • An excellent pre-workout supplement (this is a highly versatile weight loss pill)
  • Just 1 capsule per serving
  • Greater focus and willpower to lose weight
  • Consistent energy boost
  • Enhanced muscle tone
  • Better mood and sex drive
  • The ingredients may not be effective for you
  • Not as powerful as other stimulants in our Top 10
  • Side effects including stomach ache

RSP Nutrition QuadraLean Thermogenic Fat Burner

We’re big fans of RSP supplements, and the company hit another home run with its QuadraLean Thermo fat burner. This is the all-inclusive resort of fat burner supplements for men currently on the market.

QuadraLean contains 4 blends specially formulated for weight management, energy, focus, and thermogenesis. This versatile supplement will help push your weight loss journey into overdrive and break past weight-loss plateaus that might be discouraging you from continuing your journey.

Lastly, the ingredients work to burn fat, not muscle. Most men notice an increase in lean muscle mass after taking QuadraLean.

  • Super-encouraging authentic before & after photos
  • A lasting kick of clean energy to burn more calories daily
  • An effective appetite suppressant
  • No caffeine jitters for caffeine-sensitive individuals
  • Laser Focus
  • A superb addition to an intermittent fasting routine
  • Better Metabolism
  • You may still experience jitters
  • May not live up to your expectations
  • May cause stomach upset

Old School Labs Vintage Burn Muscle-Preserving Fat Burner

If you value clean supplements, it’s tough to beat the straightforward formula in Vintage Burn. The 9-ingredient fat-burning blend attacks fat from every angle while leaving lean muscle mass intact. There’s not much more you can ask for as a man who values his masculine figure.

Key ingredients Raspberry Ketones, Green Coffee Bean Extract, Garcinia Cambogia, and Green Tea Leaf Extract work to control your appetite while blocking the formation of new fat. Another advantage of Vintage Burn is the lower dose of caffeine, 150 mg compared to other fat burners with well over 200 mg.

Old School Labs is so confident in its Vintage Burn supplement that the company offers a 100% Money-Back Satisfaction Guarantee should any discomfort occur.

  • Build up a sweat without jitters
  • Men over 40 are getting some seriously awesome shredded six-pack results
  • Consistent clean energy without the rollercoaster peaks and valleys
  • Very low number of reported side effects
  • As with all natural supplements, it may not work for your body like it does for others
  • The company offers incentives
  • May cause nausea

Jacked Factory Burn-XT Thermogenic Fat Burner

Jacked Factory wasn’t kidding around when they made this blend. Be advised Burn XT contains a 270 mg dose of Caffeine anhydrous and 450 mg of Green Tea Leaf Extract per serving. On top of that, Jacked Factory added BioPerine® Black Pepper Fruit Extract for enhanced absorption.

The clear advantage of Burn XT is the MASSIVE energy and metabolism boost each serving delivers. The clear disadvantage is this supplement is undoubtedly not for men who are sensitive to caffeine or have a sensitive stomach.

Burn XT is the type of weight loss pill that gets to work starting from day 1 and keeps going to work the entire time you’re on it. We like Burn XT for men who are serious about weight loss and need that extra jolt of energy to start their weight loss journey.

  • A seriously powerful appetite suppressant
  • A top supplement for accelerating weight loss
  • Noticeable energy boost
  • Increased endurance in the gym
  • Helps to shed those stubborn pounds that like to stick around after winter
  • The high dose of caffeine may cause side effects including nausea, uneasiness, anxiety, and jitters
  • Does not work for everyone
  • Profuse Sweating Side Effect

Iron Brothers Thermo Burn

Thermo Burn is a fantastic weight loss pill for men that’s also high in caffeine like Burn XT, except Thermo Burn contains L-theanine to combat caffeine side effects. L-theanine is a naturally-occurring amino acid in green tea that promotes a calming effect.

Additional ingredients Paradoxine® aka Grains of Paradise Extract, Theobromine, Yohimbe HCL work to burn subcutaneous and visceral fat. What we like the most is the doses of each ingredient. There are no proprietary blends or underdosed active ingredients in this supplement.

In other words, Thermo Burn is for men who are determined and serious about reaching their weight loss goals.

  • Intense, yet smooth energy boost
  • More regular bowel movements
  • Noticeable reduction in body fat %
  • Awesome as a pre-workout supplement for enhanced performance in the gym
  • Outstanding alertness
  • You may experience too many trips to the pot
  • Might be too intense for you
  • May cause excessive sweating (be sure to stay hydrated)

Hydroxycut Hardcore Elite

As the name suggests, Hydroxycut Hardcore Elite is certainly not for the faint of heart. Similar to Burn XT, it’s critical to exercise caution and look before you leap when choosing Hydroxycut. Muscletech is the real McCoy, often providing clinical results to prove the effectiveness of its products.

Hardcore Elite falls in line with the quality and strength of other top Muscletech supplements and is certainly one of the best fat burning pills for men on the market. However, it’s certainly not for every man.

The key here is to assess and calculate your goals before you reach for Hardcore Elite because the journey might be a wild ride. Having said that, the 100 mg dose of L-theanine per serving is stronger than what’s found in Thermo Burn, and the chances of unwelcome side effects are slimmer than with Burn XT.

  • An energy boost that won’t allow you to be lazy
  • Serious weight loss results
  • Toned, leaner muscle mass
  • More affordable than other brands
  • Superb for suppressing an overactive appetite and cutting out unhealthy snacks
  • Common caffeine side effects (use extra caution if sensitive to caffeine)
  • May cause nausea
  • You might prefer original Hydroxycut over Hardcore Elite

Prime Labs Prime Test

Are you feeling low on testosterone? Low testosterone levels are no good and often lead to visceral fat accumulating around the gut. This type of low-T fat is nearly impossible to get rid of through diet alone.

Prime Labs Prime Test is an effective natural testosterone booster that may help you burn that stubborn fat hanging out in your gut.

Prime Labs Prime Test is caffeine-free unlike most of the other weight loss pills in our Top 10. Keep in mind, Prime Test is not specifically made for weight loss. Older men with lower testosterone levels benefit the most from Prime Test by raising T for natural weight loss.

  • Men over 50 are experiencing noticeable weight loss
  • Increased strength
  • More energy without stimulants
  • A more cut appearance
  • Effective for eliminating stubborn belly fat
  • Does not provide all men with the desired testosterone boost
  • Company offers incentives
  • It’s a proprietary blend (no exact dosages of each ingredient listed)


Now that you know the best weight loss pills for men, we’ll answer several frequently asked questions concerning how to get the most from weight loss supplements.

How do weight loss pills work?

Weight loss pills contain ingredients that work to block the accumulation and formation of fat. For example, the popular weight loss ingredient Garcinia Cambogia contains hydroxycitric acid (HCA), a component potentially responsible for Garcinia’s weight loss benefits.

While Garcinia studies are mixed, the most promising study – that supplement companies often lean on – showed that Garcinia may reduce the accumulation of belly fat in obese individuals (*).

Putting all the fancy ingredients aside, the reason the best weight loss pills often contain caffeine is that caffeine is one of the most common & effective appetite suppressants in the world. It also provides the user with a jolt of daily energy to burn more calories and fat.

Green tea extract and green coffee extract (other common ingredients across popular weight loss supplements) have also been shown to promote weight loss and thermogenesis (*).

What is thermogenesis?

Thermogenesis quite simply means the production of heat in the body (*). For this reason, most people sweat a lot more when they take thermogenic fat burners due to the spike in body heat.

Weight loss pills help the body to use more calories, boost metabolic rate, and burn fat. These are all considered thermogenic effects.

Thermogenesis combined with appetite suppression is the main reason weight loss pills really work.

However, it’s important to remember that weight loss pills don’t do all the work for you. Rarely, someone experiences significant weight loss by taking diet pills alone.

What weight loss pills are safe?

All of the weight loss pills & supplements in our Top 10 are safe, nevertheless, it’s important to always consult your doctor before starting on any new weight-loss pill or regimen.

If you’re sensitive to caffeine, it’s best to shop for stimulant-free weight loss supplements such as stim-free QuadraLean, Prime Test, or a caffeine-free fat burner such as Genius Burn.

Lastly, always pay close attention to the ingredients label to see exactly what’s in the supplement before you buy it. Companies that don’t show clear photos of the ingredients or disclose all ingredients should not be trusted.

What weight loss pills work the best?

We took the time to examine each product in our Top 10 before creating our list. We ranked the supplements by which pills work the best for men.

As we mentioned in the opener, the 1st step is to identify the cause of your weight gain. Is it low testosterone? Overeating? Lack of exercise?

Once you get to the root of the issue, it’s a lot easier to identify which weight loss pill will work the best for you. All of the weight loss pills in our guide really work, but certainly not for everyone.

These are natural supplements that affect everyone’s body differently. Joe may get tremendous results with one supplement, while Jim feels absolutely nothing.

If you try a product, and it’s a dud for you, be sure to check the label on the next supplement to ensure you’re not buying a supplement with the same ingredients and dosages.

The bottom line is to identify your goals and the cause of your weight gain before choosing a weight loss pill.

Which weight loss pills work the fastest?

Weight loss pills with higher dosages of caffeine such as Burn XT are going to go to work the fastest. While this might seem like a great idea, in theory, it’s extra important to assess your caffeine tolerance first.

Users who experience caffeine side effects often skip right to a full recommended serving without assessing their tolerance first.

To give you an idea of the caffeine content in the weight loss pills in our Top 10, a 14 oz cup of Dunkin’ Donuts Brewed Coffee contains 210 mg of caffeine (*).

Iron Brothers Thermo Burn contains 275 mg of caffeine per serving. If a 14 oz cup of Dunkin’ D’s coffee makes you feel uneasy, there’s a good chance that the 275 mg of caffeine in Thermo Burn will as well.

In conclusion, weight loss pills with more stimulant power work faster, but they’re also more likely to cause unwelcome caffeine side effects.

Bottom Line

Now you know the best weight loss pills for men currently on the market and why they work. We’re big fans of Modern Man V3 because of its potential to boost testosterone and help men cut even the most stubborn visceral fat.

Modern Man is also lighter on caffeine than most of the other supplements in our Top 10. Ashwagandha and Longjack are two of the better herbal T boosters out there that are both in Modern Man.

Depending on the level of stimulation and appetite suppression you desire, there are options in our Top 10 to suit every man’s needs. Always remember to use your head before choosing a supp to set yourself up for a better chance of weight loss success!

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